What is Codeine and how is it used?
Codeine is a member of the drug class
opiates. Opiates include all naturally occurring
drugs with morphine-like effects such as Codeine
and all semi and fully synthetic drugs with morphine-like
effects such as heroin and meperidine (Demerol).
Codeine was first discovered as a natural constituent
of opium in very small concentrations, in the
range of 0.7% - 2.5% by weight. Most Codeine
found in pharmaceutical products today is synthetically
produced via the methylation of morphine.
Codeine is normally administered:
orally
subcutaneously
intramuscularly
rectally
Codeine cannot be safely administered by intravenously as it may result in pulmonary
oedema, facial swelling, dangerous release of
histamines, and various cardiovascular effects.
It cannot be administered intranasally (snorting).
Codeine free base can be smoked on the aluminum
foil ("chasing the dragon") similarly to smoking
heroin.
What are some of the common effects of Codeine addiction
Codeine is absorbed quickly from the GI tract
and it's first pass through the liver results
in very little loss of the drug. This contrasts
with morphine in which over 90% of the drug is
metabolized in the first pass through the liver
resulting in a considerable loss of potency when
administered orally.
Narcotics induce an "opioid analgesia" by altering
the perception of pain at the spinal cord and
brain. They also affect emotional responses to
pain. Opioids have stimulating effects as well
because they block inhibitory neurotransmitters.
Repeated use of these drugs can cause long-term
changes in the way the nervous system functions and incite:
stomach bleeding
kidney damage
liver damage
"itchies"
constipation
nausea
hangover
tiny pupils
blurred vision
poor night vision
impair driving ability
lowered heart rate, blood pressure and
breathing
disorientation
convulsions
hallucinations
depression
sexual problems
agitation
tremors
seizures
Codeine symptoms and side effects of withdrawl from Codeine
The worst symptoms pass within a few days, but it can take months to feel normal.
runny nose
sweating
muscle twitching
muscle pain
headaches
irregular heartbeat
nausea and vomiting
high blood pressure
fever
insomnia
dehydration
yawning
weakness
stomach cramps |